Across TCGA pan-cancer cohorts, TMEM191A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TMEM191A data layer compared with 22 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TMEM191A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TMEM191A expression acts as an unfavorable survival marker.

UCEC are the cancer types where TMEM191A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.225	0.772	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: TMEM191A tumor-vs-normal RNA expression · all TMEM191A data types