Across TCGA patient cohorts, TMEM191A mutation is significantly associated with the RNA expression of many other genes, with 1,034 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM191A-associated genes across cancer lineages are URGCP-MRPS24, IGKV1OR2-118, and SRXN1. Each is linked with TMEM191A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM191A-to-partner and partner-to-TMEM191A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM191A→partner) and Y-score (partner→TMEM191A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	URGCP-MRPS24 →	+0.367	+3.484	<.001	<.001	3	1
UCEC	IGKV1OR2-118 →	+0.202	+2.496	.006	.001	3	1
UCEC	SRXN1 →	+0.513	+3.191	.005	.009	3	1
UCEC	MIR6859-2 →	+0.492	+2.690	<.001	.001	3	1
UCEC	NOL12 →	+0.405	+3.732	.002	<.001	3	1
UCEC	MIR7702 →	+0.263	+4.475	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,034 associations by consensus.

Exploration

TMEM191A survival (RNA) · tumor vs normal (RNA) · all TMEM191A data types