Across TCGA patient cohorts, TMEM185B mutation is significantly associated with the RNA expression of many other genes, with 303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM185B-associated genes across cancer lineages are OR4A50P, MIR375, and RNU1-42P. Each is linked with TMEM185B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM185B-to-partner and partner-to-TMEM185B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM185B→partner) and Y-score (partner→TMEM185B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR4A50P →	+0.065	+4.384	<.001	.008	3	2
CESC	MIR375 →	+0.337	+4.984	<.001	.003	3	1
CESC	RNU1-42P →	+0.323	+3.996	<.001	.005	3	1
CESC	RNA5-8SP5 →	+0.315	+4.757	<.001	.004	3	1
CESC	RNU6-737P →	+0.204	+4.384	.003	.008	3	1
CESC	RNU6-359P →	+0.257	+5.252	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 303 associations by consensus.

Exploration

TMEM185B survival (RNA) · tumor vs normal (RNA) · all TMEM185B data types