Across TCGA cell cohorts, TMEM185B mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM185B-associated genes across cancer lineages are SERPINA10, TSSK1B, and ASB17. Each is linked with TMEM185B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM185B-to-partner and partner-to-TMEM185B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM185B→partner) and Y-score (partner→TMEM185B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SERPINA10 →	+0.117	+3.912	<.001	.006	3	1
BLOOD_Leukemia	TSSK1B →	+0.009	+3.289	<.001	.009	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LARGE_INTESTINE	CWH43 →	+0.731	+3.714	<.001	.001	3	1
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1
LARGE_INTESTINE	SARAF →	+0.740	+3.125	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

TMEM185B survival (RNA) · tumor vs normal (RNA) · all TMEM185B data types