TMEM184C

Across TCGA patient cohorts, TMEM184C RNA expression is significantly associated with the protein abundance of many other proteins, with 11,303 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM184C-associated proteins across cancer lineages are SPCS3, HPF1, and ELMOD2. Each is linked with TMEM184C in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM184C-to-partner and partner-to-TMEM184C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM184C versus SPCS3 in LSCC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184C→partner) and Y-score (partner→TMEM184C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPCS3 →	-0.592	-0.370	<.001	<.001	3	5
LSCC	HPF1 →	+0.390	+0.405	<.001	<.001	3	4
BRCA	ELMOD2 →	+0.499	+0.407	<.001	<.001	3	4
UCEC	ARFIP1 →	+0.375	+0.432	<.001	.001	2	5
PDAC	SCOC →	+0.512	+0.253	<.001	.003	3	4
LSCC	CASP6 →	+0.285	+0.282	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,303 associations by consensus.

TMEM184C vs SPCS3 — LSCC

Explore this scatter interactively →