TMEM184C

Across TCGA patient cohorts, TMEM184C protein abundance is significantly associated with the RNA expression of many other genes, with 6,279 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM184C-associated genes across cancer lineages are USP38, PLA2G2C, and LYPD6B. Each is linked with TMEM184C in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM184C-to-partner and partner-to-TMEM184C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM184C versus USP38 in OV, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184C→partner) and Y-score (partner→TMEM184C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	USP38 →	+0.572	+0.383	.001	.003	3	3
OV	PLA2G2C →	+0.730	+0.582	.001	<.001	3	3
UCEC	LYPD6B →	-1.762	-0.470	<.001	.002	3	3
BRCA	SERGEF →	-0.668	-0.261	<.001	<.001	3	3
BRCA	INSYN1 →	-0.884	-0.343	.005	<.001	3	3
GBM	LINC00402 →	-0.666	-0.316	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,279 associations by consensus.

TMEM184C vs USP38 — OV

Explore this scatter interactively →