TMEM184C

Across TCGA patient cohorts, TMEM184C mutation is significantly associated with the RNA expression of many other genes, with 2,056 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM184C-associated genes across cancer lineages are RNA5SP414, RNA5SP411, and RNA5SP412. Each is linked with TMEM184C in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM184C-to-partner and partner-to-TMEM184C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by TMEM184C-low versus TMEM184C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184C→partner) and Y-score (partner→TMEM184C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+0.688	+2.670	<.001	.001	3	2
UCEC	RNA5SP411 →	+1.481	+2.586	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.966	+2.774	<.001	<.001	3	2
LUSC	RNA5SP426 →	+0.318	+7.924	<.001	.008	3	2
PRAD	RN7SKP229 →	+0.144	+7.939	<.001	.008	3	2
UCEC	RN7SL191P →	+0.224	+2.622	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,056 associations by consensus.

RNA5SP414 by TMEM184C expression — UCEC

Explore this box plot interactively →