TMEM184C

Across TCGA cell cohorts, TMEM184C mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM184C-associated genes across cancer lineages are APOL5, TACR3, and SRY. Each is linked with TMEM184C in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM184C-to-partner and partner-to-TMEM184C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APOL5 grouped by TMEM184C-low versus TMEM184C-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184C→partner) and Y-score (partner→TMEM184C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	APOL5 →	+0.015	+5.060	<.001	.001	3	1
BLOOD_Leukemia	TACR3 →	+0.048	+5.060	<.001	.001	3	1
BLOOD_Leukemia	SRY →	+0.029	+4.874	<.001	.002	3	1
BLOOD_Leukemia	SMIM23 →	+0.022	+5.569	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

APOL5 by TMEM184C expression — BLOOD_Leukemia

Explore this box plot interactively →