Across TCGA patient cohorts, TMEM184B mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM184B-associated genes across cancer lineages are eIF4E, Notch1, and Bid. Each is linked with TMEM184B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM184B-to-partner and partner-to-TMEM184B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184B→partner) and Y-score (partner→TMEM184B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.176	+3.183	.025	.009	3	2
UCEC	Notch1 →	+0.161	+1.765	.002	.014	3	2
UCEC	Bid →	+0.109	+1.874	.015	.049	3	2
UCEC	EGFR_pY1068 →	-0.214	-1.415	.023	.046	3	1
UCEC	A-Raf_pS299 →	-0.127	-2.169	.004	.003	3	1
UCEC	GATA6 →	-0.147	-2.985	.015	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

TMEM184B survival (RNA) · tumor vs normal (RNA) · all TMEM184B data types