Across TCGA cell cohorts, TMEM184B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM184B-associated genes across cancer lineages are KRT85, MS4A14, and OR10H5. Each is linked with TMEM184B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM184B-to-partner and partner-to-TMEM184B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184B→partner) and Y-score (partner→TMEM184B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KRT85 →	+0.473	+3.823	<.001	.006	3	1
LARGE_INTESTINE	MS4A14 →	+0.020	+4.054	<.001	.004	3	1
LARGE_INTESTINE	OR10H5 →	+0.016	+4.347	.002	.001	3	1
LARGE_INTESTINE	NUPR2 →	+0.323	+4.688	<.001	<.001	3	1
LARGE_INTESTINE	ARMH2 →	+0.228	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

TMEM184B survival (RNA) · tumor vs normal (RNA) · all TMEM184B data types