Across TCGA cell cohorts, TMEM184B mutation is significantly associated with the mutation status of many other genes, with 460 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM184B-associated genes across cancer lineages are SWT1, PPP2R1B, and FPGT-TNNI3K. Each is linked with TMEM184B in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM184B-to-partner and partner-to-TMEM184B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184B→partner) and Y-score (partner→TMEM184B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SWT1 →	+5.392	+5.392	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	PPP2R1B →	+5.392	+5.392	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	FPGT-TNNI3K →	+4.392	+4.954	.008	.008	1	2
LARGE_INTESTINE	ME1 →	+3.744	+5.000	<.001	<.001	1	2
LARGE_INTESTINE	FMC1-LUC7L2 →	+3.329	+3.799	.005	.005	1	2
UPPER_AERODIGESTIVE_TRACT	OTUD4 →	+5.392	+5.392	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 460 associations by consensus.

Exploration

TMEM184B survival (RNA) · tumor vs normal (RNA) · all TMEM184B data types