Across TCGA pan-cancer cohorts, TMEM183AP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TMEM183AP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TMEM183AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMEM183AP1 is over-expressed in tumor.

HNSC and KIRP are the cancer types where TMEM183AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMEM183AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.046	.016	4	view →
KIRP	Female	All	+0.089	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TMEM183AP1 RNA expression & survival · all TMEM183AP1 data types