TMEM182

Across TCGA patient cohorts, TMEM182 protein abundance is significantly associated with the RNA expression of many other genes, with 1,131 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM182-associated genes across cancer lineages are CTSG, ASB2, and SLC8A3. Each is linked with TMEM182 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM182-to-partner and partner-to-TMEM182 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM182 versus CTSG in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM182→partner) and Y-score (partner→TMEM182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CTSG →	+1.134	+0.972	.001	<.001	3	1
HNSC	ASB2 →	+1.214	+1.223	<.001	<.001	3	1
HNSC	SLC8A3 →	+0.962	+1.369	<.001	<.001	3	1
HNSC	TCL1A →	+1.017	+0.807	<.001	.004	3	1
HNSC	EEF1A2 →	+1.373	+1.065	<.001	<.001	3	1
HNSC	MYLK2 →	+1.009	+1.043	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,131 associations by consensus.

TMEM182 vs CTSG — HNSC

Explore this scatter interactively →