TMEM182

Across TCGA cell cohorts, TMEM182 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,893 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TMEM182-associated GO terms across cancer lineages are Phospholipid biosynthetic process, Regulation of myoblast fusion, and Vacuolar transport. Each is linked with TMEM182 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM182-to-partner and partner-to-TMEM182 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipid biosynthetic process grouped by TMEM182-low versus TMEM182-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM182→partner) and Y-score (partner→TMEM182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.050	+0.799	<.001	<.001	3	13
OVARY	Regulation of myoblast fusion →	+0.071	+0.775	.008	<.001	2	14
OESOPHAGUS	Vacuolar transport →	+0.065	+1.127	.008	.003	2	13
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.047	+0.631	<.001	.004	3	12
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.037	+0.749	.002	.001	3	12
OVARY	Protein localization to vacuole →	+0.066	+0.702	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,893 associations by consensus.

Phospholipid biosynthetic process by TMEM182 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →