TMEM182

Across TCGA cell cohorts, TMEM182 protein abundance is significantly associated with the RNA expression of many other genes, with 2,145 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM182-associated genes across cancer lineages are PAXBP1, EXO1, and CCDC28B. Each is linked with TMEM182 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM182-to-partner and partner-to-TMEM182 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM182 versus PAXBP1 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM182→partner) and Y-score (partner→TMEM182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PAXBP1 →	+0.942	+0.624	.005	.006	3	6
OESOPHAGUS	EXO1 →	+0.916	+0.502	.002	.008	2	5
BREAST	CCDC28B →	+1.100	+0.431	.009	.004	3	4
BREAST	ZNF496 →	+0.813	+0.573	.002	.004	3	4
BREAST	MAK16 →	+0.811	+0.457	.001	.007	3	4
BREAST	ZNF670 →	+0.757	+0.599	.009	.002	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,145 associations by consensus.

TMEM182 vs PAXBP1 — LUNG_NSCLC_LUSC

Explore this scatter interactively →