TMEM182

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TMEM182 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TMEM182-associated genes across cancer lineages are PRAMEF11. Each is linked with TMEM182 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM182-to-partner and partner-to-TMEM182 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF11 grouped by TMEM182-low versus TMEM182-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM182→partner) and Y-score (partner→TMEM182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCPRAMEF11 →+0.026+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PRAMEF11 by TMEM182 expression — LUNG_SCLC

Box plot of PRAMEF11 in TMEM182-low vs TMEM182-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration