Across TCGA pan-cancer cohorts, TMEM179B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TMEM179B data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TMEM179B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TMEM179B expression acts as an unfavorable survival marker.

UCEC and LIHC are the cancer types where TMEM179B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LIHC	DFS	Median	All	0.101	0.543	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TMEM179B tumor-vs-normal RNA expression · all TMEM179B data types