Across TCGA patient cohorts, TMEM179B mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM179B-associated genes across cancer lineages are TRAJ52, RNA5SP215, and C2orf83. Each is linked with TMEM179B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM179B-to-partner and partner-to-TMEM179B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM179B→partner) and Y-score (partner→TMEM179B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ52 →	+0.913	+2.756	<.001	.006	3	2
BLCA	RNA5SP215 →	+0.432	+5.444	<.001	.002	3	2
UCEC	C2orf83 →	+0.154	+2.640	<.001	.008	3	1
SKCM	GLUD1P9 →	+0.024	+7.816	<.001	.008	3	1
SKCM	LINC01810 →	+0.109	+7.816	<.001	.008	3	1
SKCM	RN7SL240P →	+0.149	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

TMEM179B survival (RNA) · tumor vs normal (RNA) · all TMEM179B data types