Across TCGA cell cohorts, TMEM179B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,057 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM179B-associated GO terms across cancer lineages are Mitochondrial electron transport, succinate to ubiquinone, Endoplasmic reticulum to cytosol transport, and Retrograde protein transport, ER to cytosol. Each is linked with TMEM179B in more than 12 cancer types. Because this analysis shows association rather than direction, both TMEM179B-to-partner and partner-to-TMEM179B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM179B→partner) and Y-score (partner→TMEM179B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Mitochondrial electron transport, succinate to ubiquinone →	+0.141	+0.729	<.001	.001	3	13
SOFT_TISSUE	Endoplasmic reticulum to cytosol transport →	+0.138	+0.697	<.001	<.001	3	10
SOFT_TISSUE	Retrograde protein transport, ER to cytosol →	+0.138	+0.697	<.001	<.001	3	10
OVARY	Endosome transport via multivesicular body sorting pathway →	+0.077	+0.873	<.001	<.001	3	10
LUNG_SCLC	Viral budding via host ESCRT complex →	+0.129	+0.880	<.001	<.001	3	10
LUNG_SCLC	Late endosome to vacuole transport →	+0.080	+0.664	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,057 associations by consensus.

Exploration

TMEM179B survival (RNA) · tumor vs normal (RNA) · all TMEM179B data types