TMEM176B

Across TCGA patient cohorts, TMEM176B RNA expression is significantly associated with the protein abundance of many other proteins, with 18,701 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM176B-associated proteins across cancer lineages are SASH3, ANKRD44, and APBB1IP. Each is linked with TMEM176B in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM176B-to-partner and partner-to-TMEM176B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM176B versus SASH3 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM176B→partner) and Y-score (partner→TMEM176B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SASH3 →	+0.653	+1.784	<.001	<.001	3	7
OV	ANKRD44 →	+0.555	+1.208	<.001	<.001	3	7
OV	APBB1IP →	+0.591	+1.129	<.001	<.001	3	7
UCEC	ARHGAP15 →	+0.679	+1.661	<.001	<.001	3	7
GBM	CD163 →	+0.740	+0.969	<.001	<.001	3	7
LSCC	DOCK10 →	+0.437	+0.785	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,701 associations by consensus.

TMEM176B vs SASH3 — OV

Explore this scatter interactively →