TMEM176A

Across TCGA patient cohorts, TMEM176A RNA expression is significantly associated with the protein abundance of many other proteins, with 19,112 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM176A-associated proteins across cancer lineages are WAS, WDFY4, and WIPF1. Each is linked with TMEM176A in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM176A-to-partner and partner-to-TMEM176A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM176A versus WAS in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM176A→partner) and Y-score (partner→TMEM176A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	WAS →	+0.632	+0.987	<.001	<.001	3	7
HNSC	WDFY4 →	+0.631	+1.101	<.001	<.001	3	7
HNSC	WIPF1 →	+0.502	+1.070	<.001	<.001	3	7
GBM	TNFAIP8L2 →	+0.729	+0.903	<.001	<.001	3	7
HNSC	RCSD1 →	+0.764	+1.307	<.001	<.001	3	7
LSCC	SERPINB9 →	+0.485	+0.763	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,112 associations by consensus.

TMEM176A vs WAS — HNSC

Explore this scatter interactively →