Across TCGA patient cohorts, TMEM170B RNA expression is significantly associated with the RNA expression of many other genes, with 20,730 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TMEM170B-associated genes across cancer lineages are ZYG11B, SMIM13, and NBPF9. Each is linked with TMEM170B in more than 33 cancer types. Because this analysis shows association rather than direction, both TMEM170B-to-partner and partner-to-TMEM170B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM170B→partner) and Y-score (partner→TMEM170B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	ZYG11B →	+1.296	+0.862	<.001	<.001	3	34
UVM	SMIM13 →	+1.247	+0.988	<.001	<.001	3	33
SCLC	NBPF9 →	+1.291	+1.146	<.001	<.001	3	33
UVM	SMCHD1 →	+1.480	+0.877	<.001	<.001	3	33
DLBC	HERC1 →	+0.984	+1.139	<.001	<.001	3	33
UVM	UHRF1BP1L →	+1.171	+0.862	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,730 associations by consensus.

Exploration

TMEM170B survival (RNA) · tumor vs normal (RNA) · all TMEM170B data types