Across TCGA patient cohorts, TMEM170B RNA expression is significantly associated with the protein abundance of many other proteins, with 20,003 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM170B-associated proteins across cancer lineages are MYEF2, ARF6, and NUDT3. Each is linked with TMEM170B in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM170B-to-partner and partner-to-TMEM170B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM170B→partner) and Y-score (partner→TMEM170B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYEF2 →	+0.881	+0.662	<.001	<.001	3	6
HNSC	ARF6 →	-0.462	-0.785	<.001	<.001	3	6
UCEC	NUDT3 →	+0.720	+0.772	<.001	<.001	3	6
LSCC	CDCP1 →	-0.509	-0.705	<.001	<.001	3	6
GBM	TEP1_S397 →	-0.414	-0.635	.002	<.001	3	5
HNSC	MYEF2_S17 →	+1.098	+0.690	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,003 associations by consensus.

Exploration

TMEM170B survival (RNA) · tumor vs normal (RNA) · all TMEM170B data types