Across TCGA patient cohorts, TMEM170B mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM170B-associated genes across cancer lineages are NF1P10, MIA-RAB4B, and BIVM-ERCC5. Each is linked with TMEM170B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM170B-to-partner and partner-to-TMEM170B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM170B→partner) and Y-score (partner→TMEM170B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NF1P10 →	+0.308	+3.778	<.001	.007	3	1
UCEC	MIA-RAB4B →	+0.105	+3.863	.006	.008	3	1
UCEC	BIVM-ERCC5 →	+0.016	+3.748	.003	.008	3	1
UCEC	TRGJP1 →	+0.804	+3.969	.001	.005	3	1
UCEC	TRAJ24 →	+1.360	+4.741	<.001	.001	3	1
UCEC	RNU6-907P →	+0.609	+4.666	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

TMEM170B survival (RNA) · tumor vs normal (RNA) · all TMEM170B data types