TMEM170B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TMEM170B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible TMEM170B-associated genes across cancer lineages are SERPINA7 and C1orf158. Each is linked with TMEM170B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM170B-to-partner and partner-to-TMEM170B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM170B→partner) and Y-score (partner→TMEM170B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaSERPINA7 →+0.459+4.807<.001.00631
BLOOD_MyelomaC1orf158 →+0.053+4.807<.001.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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