TMEM170A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM170A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TMEM170A-associated genes across cancer lineages are CDY1B. Each is linked with TMEM170A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM170A-to-partner and partner-to-TMEM170A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDY1B grouped by TMEM170A-low versus TMEM170A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM170A→partner) and Y-score (partner→TMEM170A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMCDY1B →+0.014+7.816<.001.00831
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CDY1B by TMEM170A expression — SKCM

Box plot of CDY1B in TMEM170A-low vs TMEM170A-high samples in SKCM.

Explore this box plot interactively →

Exploration