TMEM170A

Across TCGA cell cohorts, TMEM170A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,666 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM170A-associated GO terms across cancer lineages are Nuclear pore complex assembly, Viral transcription, and Pore complex assembly. Each is linked with TMEM170A in more than 16 cancer types. Because this analysis shows association rather than direction, both TMEM170A-to-partner and partner-to-TMEM170A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore complex assembly grouped by TMEM170A-low versus TMEM170A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM170A→partner) and Y-score (partner→TMEM170A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nuclear pore complex assembly →	+0.176	+1.331	<.001	<.001	3	17
BREAST	Viral transcription →	+0.098	+0.869	<.001	<.001	3	17
BREAST	Pore complex assembly →	+0.122	+0.960	.001	.001	3	16
SOFT_TISSUE	mRNA transport →	+0.082	+0.895	<.001	.002	3	15
BONE	mRNA export from nucleus →	+0.098	+0.833	.001	<.001	3	15
BONE	Late viral transcription →	+0.127	+0.802	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,666 associations by consensus.

Nuclear pore complex assembly by TMEM170A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →