Across TCGA patient cohorts, TMEM17 mutation is significantly associated with the RNA expression of many other genes, with 386 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM17-associated genes across cancer lineages are RNA5SP158, RNU6-756P, and MIR6853. Each is linked with TMEM17 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM17-to-partner and partner-to-TMEM17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM17→partner) and Y-score (partner→TMEM17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP158 →	+0.212	+3.879	<.001	.009	3	2
BLCA	RNU6-756P →	+0.333	+7.640	<.001	.009	3	2
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1
HNSC	RNU6-463P →	+0.363	+7.954	<.001	.008	3	1
BLCA	LSM1P2 →	+0.129	+7.640	<.001	.009	3	1
COAD	MIR615 →	+1.294	+5.693	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

Exploration

TMEM17 survival (RNA) · tumor vs normal (RNA) · all TMEM17 data types