Across TCGA cell cohorts, TMEM17 mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM17-associated genes across cancer lineages are GSK2801, Oxaliplatin, and 50869. Each is linked with TMEM17 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM17-to-partner and partner-to-TMEM17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM17→partner) and Y-score (partner→TMEM17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2801 →	+0.439	+2.649	.004	.046	3	1
LARGE_INTESTINE	Oxaliplatin →	+0.562	+2.649	.033	.046	2	1
LARGE_INTESTINE	50869 →	+0.433	+2.649	.041	.046	2	1
LARGE_INTESTINE	GSK2256098C →	+0.428	+2.906	.004	.033	1	1
LARGE_INTESTINE	LMB_AB1 →	+0.321	+2.649	.031	.046	1	1
LARGE_INTESTINE	Ibrutinib →	+0.699	+2.646	.029	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

TMEM17 survival (RNA) · tumor vs normal (RNA) · all TMEM17 data types