Across TCGA patient cohorts, TMEM167B protein abundance is significantly associated with the RNA expression of many other genes, with 8,430 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TMEM167B-associated genes across cancer lineages are MYH3, ZNF728, and ENG. Each is linked with TMEM167B in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM167B-to-partner and partner-to-TMEM167B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM167B→partner) and Y-score (partner→TMEM167B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYH3 →	-1.046	-0.245	.004	.009	3	4
UCEC	ZNF728 →	-0.682	-0.667	<.001	<.001	3	4
PDAC	ENG →	-0.587	-0.808	<.001	<.001	3	3
HNSC	RAPGEF1 →	-0.328	-0.275	.007	.002	3	3
HNSC	HRC →	-1.246	-0.300	.007	.007	3	3
HNSC	CARD6 →	-0.495	-0.267	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,430 associations by consensus.

Exploration

TMEM167B survival (RNA) · tumor vs normal (RNA) · all TMEM167B data types