TMEM163

Across TCGA cell cohorts, TMEM163 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,604 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM163-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Regulation of syncytium formation by plasma membrane fusion, and Nucleotide biosynthetic process. Each is linked with TMEM163 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM163-to-partner and partner-to-TMEM163 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribose phosphate biosynthetic process grouped by TMEM163-low versus TMEM163-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM163→partner) and Y-score (partner→TMEM163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Ribose phosphate biosynthetic process →	+0.032	+0.823	.003	.005	3	6
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.083	+2.220	.001	<.001	3	5
CNS	Nucleotide biosynthetic process →	+0.032	+0.785	.005	.004	2	6
SOFT_TISSUE	Peptidyl-threonine phosphorylation →	+0.056	+1.118	<.001	.006	3	5
SOFT_TISSUE	Peptidyl-threonine modification →	+0.056	+1.118	<.001	.006	3	5
BREAST	Regulation of myoblast fusion →	+0.079	+0.141	.009	.002	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,604 associations by consensus.

Ribose phosphate biosynthetic process by TMEM163 expression — CNS

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