TMEM161BP1

Across TCGA pan-cancer cohorts, TMEM161BP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TMEM161BP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TMEM161BP1 RNA is repressed in tumor relative to normal tissue. In most cancer types TMEM161BP1 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, BRCA, and THCA are the cancer types where TMEM161BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMEM161BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.019	.002	6	view →
BRCA	Female	All	+0.359	.002	4	view →
THCA	Male	All	−0.015	.031	2	view →
KICH	All	IV	−0.035	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

TMEM161BP1–KIRC

Open the KIRC breakdown →