TMEM161B

Across TCGA patient cohorts, TMEM161B protein abundance is significantly associated with the RNA expression of many other genes, with 1,255 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM161B-associated genes across cancer lineages are IFIT5, LINC01136, and ASXL3. Each is linked with TMEM161B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM161B-to-partner and partner-to-TMEM161B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM161B versus IFIT5 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM161B→partner) and Y-score (partner→TMEM161B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IFIT5 →	+0.714	+0.534	.008	.004	3	2
GBM	LINC01136 →	-0.385	-0.235	.009	.009	3	2
PDAC	ASXL3 →	-0.960	-0.730	.006	.005	3	2
LUAD	NCKAP5-AS2 →	-0.803	-0.313	.004	.001	3	2
GBM	MTATP8P2 →	-1.002	-0.339	.001	<.001	3	2
GBM	PHACTR3-AS1 →	-1.818	-0.391	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,255 associations by consensus.

TMEM161B vs IFIT5 — OV

Explore this scatter interactively →