TMEM161A

Across TCGA patient cohorts, TMEM161A protein abundance is significantly associated with the RNA expression of many other genes, with 11,833 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM161A-associated genes across cancer lineages are PIGX, DPP4, and AQP1. Each is linked with TMEM161A in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM161A-to-partner and partner-to-TMEM161A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM161A versus PIGX in LSCC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM161A→partner) and Y-score (partner→TMEM161A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIGX →	+0.946	+0.448	<.001	<.001	3	4
UCEC	DPP4 →	-1.144	-0.551	.001	.002	3	4
CCRCC	AQP1 →	-1.065	-0.316	<.001	.006	3	4
LSCC	TIMM13 →	+0.514	+0.377	<.001	<.001	3	4
CCRCC	PLCL1 →	-0.682	-0.507	.008	.001	3	4
HNSC	LINC02391 →	-0.571	-0.432	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,833 associations by consensus.

TMEM161A vs PIGX — LSCC

Explore this scatter interactively →