TMEM161A

Across TCGA cell cohorts, TMEM161A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,638 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM161A-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and XMP metabolic process. Each is linked with TMEM161A in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM161A-to-partner and partner-to-TMEM161A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by TMEM161A-low versus TMEM161A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM161A→partner) and Y-score (partner→TMEM161A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.090	+0.732	.004	.002	3	14
BONE	Electron transport coupled proton transport →	+0.090	+0.732	.004	.002	3	14
BLOOD_Myeloma	XMP metabolic process →	+0.148	+0.757	<.001	<.001	3	14
BLOOD_Myeloma	XMP biosynthetic process →	+0.148	+0.757	<.001	<.001	3	14
BLOOD_Myeloma	'de novo' XMP biosynthetic process →	+0.148	+0.757	<.001	<.001	3	14
BONE	Mitochondrial tRNA wobble uridine modification →	+0.148	+0.760	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,638 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by TMEM161A expression — BONE

Explore this box plot interactively →