TMEM160

Across TCGA patient cohorts, TMEM160 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,158 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM160-associated GO terms across cancer lineages are Negative regulation of IRE1-mediated unfolded protein response, Golgi ribbon formation, and Ribosome-associated ubiquitin-dependent protein catabolic process. Each is linked with TMEM160 in more than 29 cancer types. Because this analysis shows association rather than direction, both TMEM160-to-partner and partner-to-TMEM160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of IRE1-mediated unfolded protein response grouped by TMEM160-low versus TMEM160-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM160→partner) and Y-score (partner→TMEM160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Negative regulation of IRE1-mediated unfolded protein response →	-0.085	-0.997	<.001	<.001	3	30
THYM	Golgi ribbon formation →	-0.092	-1.023	<.001	<.001	3	29
SCLC	Ribosome-associated ubiquitin-dependent protein catabolic process →	-0.145	-0.735	<.001	<.001	2	30
THYM	Obsolete selective autophagy →	-0.071	-1.176	<.001	<.001	3	28
LAML	Regulation of endoplasmic reticulum tubular network organization →	-0.072	-0.670	<.001	<.001	3	28
DLBC	Regulation of platelet-derived growth factor receptor-alpha signaling pathway →	-0.093	-1.090	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,158 associations by consensus.

Negative regulation of IRE1-mediated unfolded protein response by TMEM160 expression — THYM

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