TMEM160

Across TCGA cell cohorts, TMEM160 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,793 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM160-associated GO terms across cancer lineages are Peptidyl-methionine modification, Nucleoside triphosphate biosynthetic process, and Cytoplasm protein quality control by the ubiquitin-proteasome system. Each is linked with TMEM160 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM160-to-partner and partner-to-TMEM160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-methionine modification grouped by TMEM160-low versus TMEM160-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM160→partner) and Y-score (partner→TMEM160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peptidyl-methionine modification →	+0.195	+1.550	<.001	<.001	3	14
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.108	+1.496	.003	.001	3	11
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.202	+1.859	<.001	<.001	3	10
BONE	ATP metabolic process →	+0.091	+1.522	.007	.005	2	11
BONE	Cytoplasm protein quality control →	+0.165	+1.599	<.001	<.001	3	9
SOFT_TISSUE	Negative regulation of NLRP3 inflammasome complex assembly →	+0.121	+1.980	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,793 associations by consensus.

Peptidyl-methionine modification by TMEM160 expression — BONE

Explore this box plot interactively →