TMEM160

Across TCGA cell cohorts, TMEM160 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM160-associated genes across cancer lineages are MSGN1, REG1B, and OR10W1. Each is linked with TMEM160 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM160-to-partner and partner-to-TMEM160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by TMEM160-low versus TMEM160-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM160→partner) and Y-score (partner→TMEM160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	REG1B →	+3.550	+3.196	<.001	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+3.977	<.001	.001	3	1
LARGE_INTESTINE	TFDP3 →	+0.022	+4.518	<.001	<.001	3	1
LARGE_INTESTINE	TAFA1 →	+0.274	+3.688	<.001	.002	3	1
LARGE_INTESTINE	NEXMIF →	+0.283	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MSGN1 by TMEM160 expression — LARGE_INTESTINE

Explore this box plot interactively →