TMEM156

Across TCGA cell cohorts, TMEM156 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,690 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM156-associated GO terms across cancer lineages are Positive regulation of chemotaxis, Detection of bacterial lipopeptide, and Regulation of positive chemotaxis. Each is linked with TMEM156 in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM156-to-partner and partner-to-TMEM156 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chemotaxis grouped by TMEM156-low versus TMEM156-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM156→partner) and Y-score (partner→TMEM156) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of chemotaxis →	+0.154	+3.802	<.001	<.001	3	10
BLOOD_Lymphoma	Detection of bacterial lipopeptide →	+1.049	+1.835	<.001	<.001	3	10
URINARY_TRACT	Regulation of positive chemotaxis →	+0.220	+2.025	<.001	<.001	3	9
URINARY_TRACT	Positive regulation of positive chemotaxis →	+0.220	+2.025	<.001	<.001	3	9
SKIN	Positive regulation of transmission of nerve impulse →	+1.223	+1.182	<.001	.001	3	9
CNS	Mature conventional dendritic cell differentiation →	+1.206	+1.233	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,690 associations by consensus.

Positive regulation of chemotaxis by TMEM156 expression — LIVER

Explore this box plot interactively →