TMEM150B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM150B mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM150B-associated genes across cancer lineages are mv Endothelial cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with TMEM150B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM150B-to-partner and partner-to-TMEM150B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by TMEM150B-low versus TMEM150B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM150B→partner) and Y-score (partner→TMEM150B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECmv Endothelial cells →-0.025-3.000.038.03631
UCECEndothelial cells →-0.044-3.416.021.00521
UCEClymphatic Endothelial cells →-0.026-3.129.031.01921
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

mv Endothelial cells by TMEM150B expression — UCEC

Box plot of mv Endothelial cells in TMEM150B-low vs TMEM150B-high samples in UCEC.

Explore this box plot interactively →

Exploration