TMEM144

Across TCGA cell cohorts, TMEM144 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,880 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM144-associated GO terms across cancer lineages are Negative regulation of NK T cell activation, Protein N-linked glycosylation, and Phospholipid biosynthetic process. Each is linked with TMEM144 in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM144-to-partner and partner-to-TMEM144 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of NK T cell activation grouped by TMEM144-low versus TMEM144-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM144→partner) and Y-score (partner→TMEM144) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of NK T cell activation →	+0.880	+0.720	<.001	.001	3	10
BONE	Protein N-linked glycosylation →	+0.091	+0.952	<.001	<.001	3	9
URINARY_TRACT	Phospholipid biosynthetic process →	+0.044	+1.535	.002	<.001	3	9
STOMACH	Maintenance of blood-brain barrier →	+0.155	+1.059	.001	.009	3	9
PANCREAS	Regulation of atrial cardiac muscle cell membrane depolarization →	-1.214	-0.831	.003	.002	3	9
PANCREAS	Microtubule depolymerization →	-0.119	-0.784	.002	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,880 associations by consensus.

Negative regulation of NK T cell activation by TMEM144 expression — BONE

Explore this box plot interactively →