TMEM143

Across TCGA patient cohorts, TMEM143 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,032 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM143-associated proteins across cancer lineages are TUT7, MYO1G, and PRPF31. Each is linked with TMEM143 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM143-to-partner and partner-to-TMEM143 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM143 versus TUT7 in HNSC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM143→partner) and Y-score (partner→TMEM143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TUT7 →	-0.263	-0.365	<.001	.001	3	4
GBM	MYO1G →	-0.500	-0.213	.001	.008	3	4
GBM	PRPF31 →	+0.238	+0.261	.001	.001	3	4
HNSC	MSI2 →	+0.448	+0.413	<.001	<.001	3	4
BRCA	RIPK2 →	-0.348	-0.504	<.001	<.001	3	4
GBM	DOK3 →	-0.503	-0.285	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,032 associations by consensus.

TMEM143 vs TUT7 — HNSC

Explore this scatter interactively →