TMEM143

Across TCGA cell cohorts, TMEM143 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,631 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM143-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with TMEM143 in more than 12 cancer types. Because this analysis shows association rather than direction, both TMEM143-to-partner and partner-to-TMEM143 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by TMEM143-low versus TMEM143-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM143→partner) and Y-score (partner→TMEM143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.107	-0.824	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.107	-0.824	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.110	-0.824	<.001	<.001	3	13
STOMACH	Positive regulation of sphingolipid biosynthetic process →	+0.156	+1.007	<.001	<.001	3	12
OESOPHAGUS	Sperm motility →	-0.150	-0.907	<.001	.009	3	12
STOMACH	Positive regulation of ceramide biosynthetic process →	+0.156	+1.007	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,631 associations by consensus.

Cilium or flagellum-dependent cell motility by TMEM143 expression — UPPER_AERODIGESTIVE_TRACT

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