TMEM141

Across TCGA patient cohorts, TMEM141 protein abundance is significantly associated with the RNA expression of many other genes, with 5,124 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM141-associated genes across cancer lineages are MRRF, TRUB2, and BTK. Each is linked with TMEM141 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM141-to-partner and partner-to-TMEM141 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM141 versus MRRF in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM141→partner) and Y-score (partner→TMEM141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MRRF →	+0.611	+0.611	<.001	<.001	3	3
LSCC	TRUB2 →	+0.416	+0.369	<.001	<.001	3	3
LUAD	BTK →	-0.899	-1.173	.001	.004	3	3
LUAD	CNRIP1 →	-0.760	-1.034	.006	.003	3	3
LUAD	MYCT1 →	-0.960	-1.131	.003	.004	3	3
LUAD	RHOJ →	-1.151	-0.944	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,124 associations by consensus.

TMEM141 vs MRRF — LSCC

Explore this scatter interactively →