TMEM141

Across TCGA cell cohorts, TMEM141 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,131 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TMEM141-associated GO terms across cancer lineages are Organic acid catabolic process, Carboxylic acid catabolic process, and Alcohol metabolic process. Each is linked with TMEM141 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM141-to-partner and partner-to-TMEM141 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organic acid catabolic process grouped by TMEM141-low versus TMEM141-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM141→partner) and Y-score (partner→TMEM141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Organic acid catabolic process →	+0.074	+1.630	<.001	.001	3	9
LIVER	Carboxylic acid catabolic process →	+0.074	+1.630	<.001	.001	3	9
LARGE_INTESTINE	Alcohol metabolic process →	+0.042	+1.149	<.001	<.001	3	9
LIVER	Proteinogenic amino acid metabolic process →	+0.109	+1.778	<.001	<.001	3	8
LIVER	Regulation of actin filament-based movement →	+0.182	+1.582	<.001	<.001	3	8
LIVER	Positive regulation of vitamin D receptor signaling pathway →	+0.268	+1.535	.003	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,131 associations by consensus.

Organic acid catabolic process by TMEM141 expression — LIVER

Explore this box plot interactively →