TMEM138

Across TCGA patient cohorts, TMEM138 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,694 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM138-associated proteins across cancer lineages are CPSF7, UBXN1, and NXF1. Each is linked with TMEM138 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM138-to-partner and partner-to-TMEM138 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM138 versus CPSF7 in HNSC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM138→partner) and Y-score (partner→TMEM138) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CPSF7 →	+0.355	+0.642	<.001	<.001	3	7
HNSC	UBXN1 →	+0.312	+0.555	<.001	<.001	2	6
GBM	NXF1 →	+0.386	+0.314	<.001	<.001	3	4
PDAC	WRAP53_S491 →	+0.774	+0.239	<.001	<.001	3	3
GBM	YTHDC1 →	+0.362	+0.285	<.001	.001	3	3
LSCC	SRP54 →	-0.188	-0.311	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,694 associations by consensus.

TMEM138 vs CPSF7 — HNSC

Explore this scatter interactively →