TMEM134

Across TCGA patient cohorts, TMEM134 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,976 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM134-associated proteins across cancer lineages are PRDM1_S272, PTPRF, and DPP3. Each is linked with TMEM134 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM134-to-partner and partner-to-TMEM134 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM134 versus PRDM1_S272 in LSCC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM134→partner) and Y-score (partner→TMEM134) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRDM1_S272 →	-0.853	-0.387	<.001	<.001	3	4
LSCC	PTPRF →	+0.558	+0.381	<.001	<.001	3	4
BRCA	DPP3 →	+0.299	+0.780	<.001	<.001	3	4
LUAD	ARHGEF1 →	-0.200	-0.436	.001	.001	3	3
LSCC	PLCG2 →	-0.691	-0.482	<.001	<.001	3	3
LSCC	RASGRP2_S576 →	-0.892	-0.420	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,976 associations by consensus.

TMEM134 vs PRDM1_S272 — LSCC

Explore this scatter interactively →