TMEM134

Across TCGA patient cohorts, TMEM134 protein abundance is significantly associated with the RNA expression of many other genes, with 10,186 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM134-associated genes across cancer lineages are ERGIC1, KIF15, and FANCB. Each is linked with TMEM134 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM134-to-partner and partner-to-TMEM134 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM134 versus ERGIC1 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM134→partner) and Y-score (partner→TMEM134) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ERGIC1 →	+0.973	+0.792	<.001	.002	3	4
UCEC	KIF15 →	-0.946	-0.487	<.001	<.001	3	4
LSCC	FANCB →	-0.656	-0.383	.003	.001	3	4
GBM	CCDC18 →	-0.549	-0.316	.002	.003	3	4
BRCA	HAUS8 →	-0.591	-0.425	<.001	.002	3	4
LSCC	TAF5 →	-0.410	-0.322	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,186 associations by consensus.

TMEM134 vs ERGIC1 — OV

Explore this scatter interactively →