TMEM132D-AS2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, TMEM132D-AS2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TMEM132D-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TMEM132D-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMEM132D-AS2 is over-expressed in tumor.

HNSC and THCA are the cancer types where TMEM132D-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMEM132D-AS2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllAll+0.023.0411view →
THCAAllAll+0.008.0291view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TMEM132D-AS2–HNSC

Tumor-vs-normal expression box plot for TMEM132D-AS2 RNA in HNSC.

Open the HNSC breakdown →

Exploration