TMEM132D-AS1

Across TCGA pan-cancer cohorts, TMEM132D-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TMEM132D-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TMEM132D-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TMEM132D-AS1 expression acts as an unfavorable survival marker, although some lineages such as GBM and ACC show a favorable association.

UCEC, UVM, and COAD are the cancer types where TMEM132D-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.506	0.736	<.001	80	view →
UVM	DFS	Tertile	II,III,IV	0.441	0.794	.002	78	view →
COAD	DFS	Tertile	II,III,IV	0.249	0.625	.003	66	view →
CESC	DFS	Tertile	II,III,IV	0.571	0.810	.009	66	view →
STAD	OS	Quartile	IV	0.288	0.786	<.001	50	view →
LIHC	OS	Quartile	All	0.355	0.553	.004	49	view →
BLCA	DFS	Quartile	II,III,IV	0.517	0.649	.003	37	view →
THYM	DFS	Tertile	All	0.103	0.857	<.001	36	view →
LUSC	OS	Tertile	All	0.545	0.803	<.001	34	view →
ESCA	OS	Quartile	All	0.525	0.787	.001	28	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
CHOL	OS	Tertile	All	0.269	0.626	.028	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

TMEM132D-AS1–UCEC (DFS)

Open the UCEC breakdown →